General malaise means that your body is very tired. The examination is divided into physical illness, mental illness, and a combination of these. A detailed medical history and simple tests are enough to make a diagnosis in most cases. The following are assumed as diseases.

・ Infectious disease (acute)

・ Infectious diseases (subacute to chronic) (tuberculosis, HIV, infective endocarditis, etc.)

・ Mental illness (depression, somatization disorder, panic disorder, stress, bereavement of a loved one, etc.)

・ Irregular consumers

·Diabetes mellitus

・ Fulminant type 1 diabetes

·hyperthyroidism

​ ・ Hypothyroidism

・ Adrenal insufficiency

・ Hyperparathyroidism

・ Electrolyte imbalance, acidosis

・ Post-infection fatigue (sequelae of new coronavirus infection, etc.)

·anemia

​ ・ Organ failure

・ Drug-induced (drugs that cause drowsiness, drugs that cause muscle weakness, drugs that lower blood pressure and lightheadedness)

・ Iron deficiency without anemia

·Malignant tumor

・ Collagen disease (especially polymyalgia rheumatica)

・ Neuromuscular disease

·alcohol

・ Sleep apnea syndrome

·pregnancy

·menopause

・ Chronic fatigue syndrome

・ Fibromyalgia

・ Cerebrospinal fluid leakage (low cerebrospinal pressure syndrome)